The EOSC4Cancer initiative aims to revolutionize cancer research by integrating diverse datasets across Europe. Focusing on genomics, imaging, medical, clinical, and socio-economic data, it enhances existing systems for secure sharing and processing of FAIR cancer data. This project, involving cancer research centers, infrastructures, hospitals, and supercomputing centers from 14 countries, seeks to provide curated datasets for advanced analytics, including machine learning. EOSC4Cancer aligns with the European Cancer Mission, engaging international coalitions and patient associations for sustainable impact. We play a pivotal role in project management, outreach, and developing business models to ensure long-term success.