The XpanDH project, funded by the EU, seeks to enhance interoperability in digital health solutions across Europe using the EEHRxF. It aims to build capacity in individuals and organizations, developing technical specifications and resources for EEHRxF, establishing the X-Bundle Readiness model, and verifying its real-world usefulness. The project targets the creation of a pan-European digital health ecosystem, focusing on solution providers and end-users. It also aims to develop a sustainable framework for a European Health Union, drawing on past eHealth interoperability projects and recommendations from DigitalHealthEurope. The consortium, with 26 digital health actors, aims to foster a vibrant pan-European (Digital) Health space by promoting EEHRxF adoption and improving healthcare cooperation.